Fig. 4: Evidence for the intragenomic recombination of adenylation domains.

a DNA phylogeny of the external region of the adenylation domains, showing the close relationship of the major parent, wolG2 A2, and the recombinant, wolG1 A2. b DNA phylogeny of the internal region of the adenylation domains, showing the close relationship of the minor parent, rmoG A, and the recombinant, wolG1 A2. c Nucleotide identity between the three adenylation domains based on a 50 nucleotide sliding window. d Topology of an adenylation domain based on ref. ¹⁰⁴, showing the predicted recombination sites Y116 and G343. Features are colour-coded according to panel a.