Fig. 1: Orgo-Seq framework to identify cell type-specific co-expressed driver genes. | Nature Communications

Fig. 1: Orgo-Seq framework to identify cell type-specific co-expressed driver genes.

From: Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder

Fig. 1

A Figure illustrating the strengths and weaknesses of bRNA-seq and scRNA-seq, and what Orgo-Seq can achieve by integrating both types of datasets. B A schematic of the Orgo-Seq framework to integrate bRNA-seq data from patient-derived brain organoids with scRNA-seq data from control brain organoids, for the discovery of critical cell types and cell type-specific driver genes.

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