Fig. 4: Viral replication is reduced in all vaccinated NHP following SARS-CoV-2 challenge. | Nature Communications

Fig. 4: Viral replication is reduced in all vaccinated NHP following SARS-CoV-2 challenge.

From: Low-dose self-amplifying mRNA COVID-19 vaccine drives strong protective immunity in non-human primates against SARS-CoV-2 infection

Fig. 4

Subgenomic RNA levels determined by RT-qPCR at specified timepoint post SARS-CoV-2 challenge for each animal in A bronchial alveolar lavage, B oropharyngeal swab, or C nasal swab. LOD = 422, samples below LOD set to ½ LOD. Geometric mean and SD. Numbers above each bar are numbers of NHP with viral load levels >LOD. Additional timepoints post complete clearance of viral RNA from vaccinated animals are not shown for clarity, full dataset provided in Supplementary tables.

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