Fig. 3: Cryo-EM structure of the homodimeric globular domain of EXTL3. | Nature Communications

Fig. 3: Cryo-EM structure of the homodimeric globular domain of EXTL3.

From: The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis

Fig. 3

EXTL3∆N was purified and subjected to cryo-EM single particle analysis, achieving a resolution of 2.4 Å. a Cryo-EM density map. Domains are coloured-coded as in Fig. 1a (GT47: dark grey; inter-domain linker: yellow; GT64 blue). b Fitted model, coloured-coded as in panel a. The N- and C-termini are labelled for each chain.

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