Fig. 1: Mutational landscape of pediatric and adult BL.
From: Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age
In total, 191 pediatric and 97 adult patient samples were analyzed. Mutations with ≥10% cohort frequency are displayed. A In total, 14 recurrently mutated genes were found in the pediatric cohort, with ID3 being the most frequently altered gene. The color code indicates mutation types or clinical data classes (see legend). B In the adult cohort, 17 recurrently mutated genes were detected. In particular, YY1AP1 and BCL2 were unmutated or less frequently mutated in the pediatric cohort.
