Fig. 4: Mutational frequencies associated with clinical characteristics.
From: Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age
For the pediatric cohort, gene mutation rates were associated with the following clinical characteristics: age dependency (A); sex (B); BM (bone marrow, C); B-AL vs. BL (D); and, central nervous system (CNS, E). F shows the sex-specific differences in the adult cohort. FOXO1, BCL2, and CREBBP are predominantly found in the female cohort, while MYC, SMARCA4, and DDX3X are overrepresented in the male cohort (P values by one-sided exact Fisher tests, see Supplementary Data 8 for all P values and FDRs, *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001.
