Fig. 1: PDAC Cell Lines display heterogeneity at single-cell level.
From: Occult polyclonality of preclinical pancreatic cancer models drives in vitro evolution
a Uniform manifold approximation projection (UMAP) plot of single cells from PDAC cell lines used in this study. b UMAP Feature Plotting for known cell-type markers (EPCAM, MUC1 for epithelial; vimentin, and KRT8 for mesenchymal cellular origin). c, d Representative scCNV plots for cell lines. Columns indicate chromosomes (numbers labeled in gray and white), rows indicate individual cells organized into clonal clades. Phylogeny determined using 10× Genomics scCNV analysis software.
