Fig. 6: VC_818_0 infects Roseburia and Blautia, and carries possible auxiliary metabolic genes.
From: Gut virome profiling identifies a widespread bacteriophage family associated with metabolic syndrome
a Whole-genome alignment of three prophages contained within VC_818_0, with pie charts denoting the top BLASTp hit of all host genes on the contigs. The mean coverage of host-derived regions in NODE_38 (p = 0.042) (b) and NODE_192 (p = 5.1 × 10−4) (c). n = 97/n = 99 biologically independent samples for MetS and controls, respectively. Significance according to two-sided Wilcoxon signed-rank test, p-values are denoted as follows * ≤ 0.05, ** ≤0.01, *** ≤ 0.001, **** ≤ 0.0001. Box plots show the median (middle line), 25th, and 75th percentile (box), with the 25th percentile minus and the 75th percentile plus 1.5 times the interquartile range (whiskers), and outliers (single points). Source data are provided as a Source Data file.
