Fig. 1: Phylogenetic distribution of V. cholerae O139. | Nature Communications

Fig. 1: Phylogenetic distribution of V. cholerae O139.

From: Vibrio cholerae O139 genomes provide a clue to why it may have failed to usher in the eighth cholera pandemic

Fig. 1

a V. cholerae species phylogenetic tree constructed from a core gene SNP multiple sequence alignment. Colored branches represent V. cholerae serogroup O1 outbreak clades named as per previous publications, as labeled. Non-7PET V. cholerae O139 genomes are highlighted as black tree tips and the 7PET lineage is boxed. b Maximum likelihood phylogenetic tree of selected V. cholerae 7PET genomes. V. cholerae O139 (n = 418) genomes were placed into the context of the 7PET phylogeny using representatives from waves 1–3 (n = 259). The O139 sublineage is shown as a dashed box within the tree. Tree tips are colored by place of isolation (see key). Color bars depict the serogroup, transmission waves and year of isolation (see key). The tree was constructed from SNPs called against the V. cholerae N16961 reference genome and a pre-7PET isolate, M66, was used as an out-group to root the tree. Recombination events were removed using Gubbins. The scale bar represents the number of substitutions per site per genome.

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