Table 1 Description of samples in the study.
From: The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia
Lines | Gender | Age (years) | Genetics | Diagnosis | hiPSC reprogramming facility | Deletion Start | Deletion End | Deletion Length (bp) | Deletion Type | Notes |
|---|---|---|---|---|---|---|---|---|---|---|
SCBB-1827 | Female | 60+ | Control | Control | In house | NA | NA | NA | NA | Used in Pilot study |
SCBB-1828 | Male | 40–59 | Control | Control | In house | NA | NA | NA | NA | Used in Pilot study |
SCBB-228 | Female | 20–39 | Control | Control | NYSCF | NA | NA | NA | NA | |
SCBB-229 | Male | 20–39 | Control | Control | NYSCF | NA | NA | NA | NA | |
SCBB-243 | Male | 20–39 | Control | Control | NYSCF | NA | NA | NA | NA | |
SCBB-258 | Female | 60+ | Control | Control | NYSCF | NA | NA | NA | NA | |
SCBB-269 | Male | 20–39 | Control | Control | NYSCF | NA | NA | NA | NA | |
SCBB-800 | Female | 40–59 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-799 | Female | 20–39 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-798 | Male | 20–39 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-803 | Female | 60+ | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1480 | Male | 40–59 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1485 | Male | 60+ | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1489 | Female | 60+ | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1473 | Male | 40–59 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1645 | Female | 40–59 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1477 | Female | 20–39 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1478 | Male | 20–39 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1646 | Male | 40–59 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1647 | Female | 20–39 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1479 | Male | 60+ | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1648 | Female | 40–59 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1471 | Female | 20–39 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1472 | Male | 40–59 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1483 | Male | 40–59 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1481 | Female | 20–39 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-652 | Male | 40–59 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-653 | Female | 40–59 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1438 | Male | 40–59 | Control | Control | Harvard iPS core | NA | NA | NA | NA | |
SCBB-1825 | Male | 40–59 | 22q11.2del | Schizophrenia | in house | 18655798 | 21726191 | 3070393 | LCR22A-D | Used in Pilot study |
SCBB-1445 | Male | 40–59 | 22q11.2del | Schizophrenia | NYSCF | 18650803 | 21800227 | 3149424 | LCR22A-D | |
SCBB-1962 | Female | 40–59 | 22q11.2del | Schizophrenia | in house | 18875445 | 21461607 | 2586162 | LCR22A-D | Used in Pilot study |
SCBB-1530 | Female | 10–19 | 22q11.2del | Mild ID, anxiety, psychosis | NYSCF | 18650726 | 21800227 | 3149501 | LCR22A-D | |
SCBB-1961 | Male | 2–9 | 22q11.2del | Autism Spectrum Disorder, ID | Stanford | 19470249 | 21028007 | 1557758 | LCR22A-B | |
SCBB-1960 | Male | 20–39 | 22q11.2del | Schizophrenia, Anxiety | Stanford | 18875445 | 21563155 | 2687710 | LCR22A-D | |
SCBB-1430 | Male | 60+ | 22q11.2del | Schizophrenia | NYSCF | 18892575 | 19026633 | 134058 | NA | |
SCBB-1524 | Male | 40–59 | 22q11.2del | Schizophrenia | NYSCF | 18650803 | 21799719 | 3148916 | LCR22A-D | |
SCBB-1434 | Male | 40–59 | 22q11.2del | Schizophrenia | NYSCF | 18650803 | 21799719 | 3148916 | LCR22A-D | |
SCBB-1437 | Female | 20–39 | 22q11.2del | Schizophrenia | NYSCF | 18797591 | 21809133 | 3011542 | LCR22A-D | |
SCBB-290 | Male | 60+ | 22q11.2del | Mild ID | Harvard iPS core | 18650726 | 21800227 | 3149501 | LCR22A-D | |
SCBB-963 | Male | 40–59 | 22q11.2del | Moderate ID, Schizophrenia | Harvard iPS core | 18637094 | 21726191 | 3089097 | LCR22A-D | |
SCBB-937 | Female | 20–39 | 22q11.2del | Mild ID, Anxiety | Harvard iPS core | 18889969 | 21563155 | 2673186 | LCR22A-D | |
SCBB-801 | Male | 2–9 | 22q11.2del | Mild ID | Harvard iPS core | 18655798 | 21804903 | 3149105 | LCR22A-D | |
SCBB-1652 | Female | 40–59 | 22q11.2del | Schizophrenia | Harvard iPS core | 18650746 | 21799719 | 3148973 | LCR22A-D | |
SCBB-1499 | Male | 20–39 | 22q11.2del | Moderate ID, Schizophrenia | Harvard iPS core | 18650746 | 21799719 | 3148973 | LCR22A-D | |
SCBB-1500 | Female | 40–59 | 22q11.2del | Moderate-Severe ID, Anxiety, Psychosis | Harvard iPS core | 18650803 | 21799719 | 3148916 | LCR22A-D | |
SCBB-1503 | Male | 20–39 | 22q11.2del | Moderate ID, Schizophrenia | Harvard iPS core | 18650746 | 21799719 | 3148973 | LCR22A-D | |
SCBB-1504 | Male | 20–39 | 22q11.2del | Moderate ID, Depression | Harvard iPS core | 18801657 | 21799890 | 2998233 | LCR22A-D | |
SCBB-1490 | Female | 10–19 | 22q11.2del | Mild ID | Harvard iPS core | 18650746 | 21799719 | 3148973 | LCR22A-D | |
H1-A | Male | NA | Control | NA | NA (hESC) | NA | NA (hESC) | NA | NA | isogenic lines |
H1-D | Male | NA | Control | NA | NA (hESC) | NA | NA (hESC) | NA | NA | isogenic lines |
H1-E | Male | NA | 22q11.2del | NA | NA (hESC) | 18924956 | 21460220 | 2535264 | LCR22A-D | isogenic lines |
H1-G | Male | NA | 22q11.2del | NA | NA (hESC) | 19175095 | 21460220 | 2285125 | LCR22A-D | isogenic lines |
