Fig. 6: Adverse reactions 7 days after each dose of BNT162b2 and CoronaVac were solicited from adolescents in the healthy safety population. | Nature Communications

Fig. 6: Adverse reactions 7 days after each dose of BNT162b2 and CoronaVac were solicited from adolescents in the healthy safety population.

From: Immunogenicity and reactogenicity of SARS-CoV-2 vaccines BNT162b2 and CoronaVac in healthy adolescents

Fig. 6

In the adolescent healthy safety population, pain at the injection site was the most common adverse reaction (ARs) reported for both vaccines, which was significantly more for those who received BNT162b2 (N = 116) than CoronaVac (N = 123) (B: 89.7% vs C: 54.5%, P < 0.0001; BB: 87.9% vs CC: 52.9%, P < 0.0001). BNT162b2 was also associated with more reporting of several other ARs, including swelling, erythema, induration and pruritis at the injection site, headache, fatigue, myalgia, nausea, diarrhoea, vomiting, arthralgia, chills, fever, reduced appetite, and abdominal pain. More participants had antipyretics use after either dose of BNT162b2 than CoronaVac (B: 9.5% vs C: 1.6%, P = 0.009; BB: 22.4% vs CC: 0.8%, P < 0.0001). Data are shown as percentages and error bars show two-sided 95% CI of the total frequency of the respective AR of any severity. CI confidence interval, B 1 dose of BNT162b2, BB 2 doses of BNT162b2, C 1 dose of CoronaVac, CC 2 doses of CoronaVac. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.

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