Fig. 1: Overall structures of NKA in the E1·3Na and E1·3Na·ATP states.
From: Cryo-EM structures of recombinant human sodium-potassium pump determined in three different states
a The overall cryo-EM map (left panel) and two views of the overall structure (middle and right panel) of the E1·3Na state. The α1 subunit is rainbow coloured from blue for the N-terminus to red for the C-terminus. β1 subunit is coloured grey. γ2 subunit is coloured pale green. b is the same as (a) but for the E1·3Na·ATP state (coloured as a spectrum from blue for the N-terminus to magenta for the C-terminus). Na+ are coloured cyan or yellow in (a) or (b), respectively. Mg2+ are coloured forest green or green in (a) or (b), respectively. The glycosylation moieties are shown as sticks. e extracellular, c cytosolic, M transmembrane helix.
