Fig. 1: E. coli biofilm and synthesis of its representative matrix components. | Nature Communications

Fig. 1: E. coli biofilm and synthesis of its representative matrix components.

From: Synthetic phosphoethanolamine-modified oligosaccharides reveal the importance of glycan length and substitution in biofilm-inspired assemblies

Fig. 1

a Cartoon representation of E. coli biofilm. b Representative synthesis of a pEtN hexasaccharide. AGA includes cycles of glycosylation, capping, and Fmoc deprotection. A final Lev deprotection liberates the hydroxyl groups that are functionalized in post-AGA steps. Reaction conditions for AGA are reported in the SI. PivCl = pivaloyl chloride, py = pyridine, MeONa = sodium methoxide. c Collection of oligosaccharides synthesized in this work. d Chemical structure of the peptide R5.

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