Fig. 4: Application of SIFT-seq to plasma.
From: A metagenomic DNA sequencing assay that is robust against environmental DNA contamination
Heatmaps of the abundance of species identified in plasma from COVID-19 patients with and without culture confirmed (a) lung and (b) blood infection, before and after application of SIFT-seq filter (black * indicates agreement with culture; HCMV: Human cytomegalovirus, HSV-1: Herpes simplex virus 1). c A heatmap of abundance of species identified in the sepsis cohort before and after SIFT-seq filtering (black * indicates species identified by blood culture). d Barplot of the prevalence of Epstein-Barr Virus (EBV), Torque teno virus (TTV), malaria-causing, or shigellosis-causing microorganisms in different patient cohorts. e Heatmap of the abundance of species identified in matched stool and plasma cfDNA samples in patients diagnosed with Crohn’s disease or ulcerative colitis. f Schematic for matched stool and plasma samples from individuals before and after medical therapy. g Heatmap of the change in abundance of gut-specific bacteria before and after treatment. Source data are provided as a source data file.
