Fig. 4: Mechanical properties of the microneedles. | Nature Communications

Fig. 4: Mechanical properties of the microneedles.

From: Programmable CRISPR-Cas9 microneedle patch for long-term capture and real-time monitoring of universal cell-free DNA

Fig. 4

a The schematic for four regions of the MNs, each group of 25 needles. b Histological analysis of piglet skin after MNs administration, stained with HE, the black arrow referring to the direction of microneedles insertion, the black short dash box referring to the region of magnification photograph (×400). c The depth of MNs penetration into piglet skin, collected from four regions, data presented as mean values ± SD, n = 3 independent experiments. d The compression tests for the microneedle arrays with different loading forces, using 1 kN force sensor. e The evaluation of mechanical strength for the microneedle arrays, the maximum stress data collected from (d), data presented as mean values ± SD, n = 3 independent experiments.

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