Fig. 2: Differentially accessible peaks are cluster and lineage-specific in the mouse embryonic forebrain.

a Embryonic snATAC-Seq dot plot of differentially accessible peaks (DA peaks) for each cluster. Dot diameter indicates the percent of DA peaks from one cluster (column cluster labels) which are detectable in any other cluster (row cluster labels). Color intensity represents the total DA peak count per cluster. Hierarchical clustering was performed using correlation distance and average linkage. Names of representative cluster-enriched transcription factor binding motifs in DA peaks are listed to the right of the dot plot. b–e UMAP plots of nuclei colored by ChromVAR global motif deviations (Z-scores) for NR2F1, ASCL1, EMX1, and NEUROD2.