Fig. 7: Mechanistic investigation and gram-scale synthesis.
From: Divergent synthesis of benzazepines and bridged polycycloalkanones via dearomative rearrangement
a Control experiments: The Eqs. 1 and 2 indicate that no radical is involved in the (homo-)hetero-Claisen rearrangement. Eq. 3 is robust and radical mediated Brandi cyclization occurred, which imply the absence of radical species in the homo-hetero-Claisen rearrangement. b Investigation of the cascade reaction profiles by the in situ IR spectroscopy. THF = tetrahydrofuran. Ts = p-toluenesulfonyl.
