Fig. 9: The antiviral activity.
From: Divergent synthesis of benzazepines and bridged polycycloalkanones via dearomative rearrangement
a 13 inhibited the growth of HIV-1 virus in dose dependent manner in SupT1 cell; b 13 exhibited moderate cytotoxicity with CC50 of 8.22 µM for SupT1 cell; c 4a inhibited the growth of IAV virus in dose dependent manner in 293T-GLUC cell; d 4a exhibited low cytotoxicity for 293T-GLUC cell. (n = 3). Bar = mean. Error bars = ±SEM. Data are from at least three independent experiments and evaluated via Prism (version 5.01, GraphPad Software, San Diego, CA, USA).
