Fig. 7: Loss of Camk4 in macrophages alleviates IMQ-induced psoriatic inflammation. | Nature Communications

Fig. 7: Loss of Camk4 in macrophages alleviates IMQ-induced psoriatic inflammation.

From: Calcium/calmodulin-dependent protein kinase IV promotes imiquimod-induced psoriatic inflammation via macrophages and keratinocytes in mice

Fig. 7

a Representative photos of mouse back skin. b Scoring curves of back skin thickness, scaling, and erythema. c H&E staining of skin sections. Scale bar = 200 μm. d Statistical analysis of epidermal thickness. e Quantitative PCR analysis of pathogenic factors in the skin of IMQ-treated mice (n = 4 biologically independent samples). f, g The percentages and numbers of neutrophils, F4/80+CD11c+ cells, CD11b+ DCs, and MHC II+ macrophages in the skin. a–e, f, g N = 6 per group from two independent experiments. Data are shown as mean ± SD. For (b, d, f, g), two-sided unpaired Student’s t test; for (e), two-sided Mann–Whitney test and two-sided unpaired Student’s t test. Source data are provided as a Source Data file.

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