Fig. 2: Acetate scavenging and Bacteroides strains are upregulated while alcohol dehydrogenation is not changed in alcohol (red) fed mice compared to controls (blue).
From: Acetate reprograms gut microbiota during alcohol consumption
a Compositional biplot of Aitchison distances on bin abundance (left) and expression (right) between conditions with arrows colored by Phylum level taxonomy. b The log-ratio of Bacteroidetes and Enterococcaceae strains (y-axes) identified in biplot for bin abundance (left) and expression (right) compared between treatment groups (x-axes). c Microbial alcohol dehydrogenase (left) and acetaldehyde dehydrogenase (right) log-ratios compared between treatments (x-axes). d Conversion in acetate switch for dissimilation (left) or excretion (right) log-ratios (y-axes) compared between treatments (x-axes). Serum short-chain fatty acids (SCFAs) (y-axis) after ethanol-feeding (x-axes) for (e) acetate, (e top left) butyrate, (e bottom left) propionate, (e top right) isovalerate, and (e bottom right) valerate. Box plots represent the minimum, maximum, median, first, and third quartile values (shaded region). Significance was evaluated by a two-sided Wilcoxon rank sum test with Tukey’s HSD post-hoc test adjusted p values of less than 0.05 were shown in the figure (N = 14). Source data are provided as a Source Data file.
