Fig. 2: ACS101 neutralization breadth and potency is inferior to those of IOMA and VRC01. | Nature Communications

Fig. 2: ACS101 neutralization breadth and potency is inferior to those of IOMA and VRC01.

From: Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein

Fig. 2

Breadth is indicated as the percentage of viruses that were neutralized. a Neutralization IC50 profile of ACS101, IOMA and VRC01 against a panel of (n = 119) Tier-2 viruses. Each symbol represents a unique HIV-1 isolate. Data for IOMA and VRC01 were derived from CATNAP78. b Overview of neutralization by ACS101 against viruses from all tested panels (147 viruses in total). Breadth of ACS101 against viruses from different clades is shown with the geometric mean (potency) in μg/ml.

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