Table 1 Subunit interactions in the VSV nucleocapsid

From: Visualizing molecular interactions that determine assembly of a bullet-shaped vesicular stomatitis virus particle

Intra-layer N contacts

 

IAa (Å2)

Lateral intra-layer contacts

  

  Interface 1

Single stranded RNA bound to N subunit

1055

  Interface 2

Ni N-terminal arm interacts with Ni-1 C-terminal lobe and with Ni-2 extended loop

793, 354

  Interface 3

Ni extended loop interacts with Ni+1 C-terminal lobe and with Ni+2 N-terminal arm

683, 354

  Interface 4

Ni N-terminal lobe interacts with Ni+1 N-terminal lobe

442

  Interface 5

Ni C-terminal lobe interacts with Ni+1 C-terminal lobe

207

Axial intra-layer contacts

  

  Interface A

Ni subunit interacts with Ni+39 subunit

94

  Interface B

Ni subunit interacts with Ni+38 subunit

18

Intra-layer M1 contacts

 

IA (Å2)

Lateral intra-layer contacts

  

 Interface 6

M1i globular domain interacts with M1i+1 globular domain

65

Axial intra-layer contacts

  

  Interface C

M1i self-association motif interacts with M1i-38 globular domain

400

  Interface D

M1i globular domain interacts with M1i+39 globular domain

78

Intra-layer M2 contacts

 

IA (Å2)

Axial intra-layer contacts

  

  Interface E

M2i globular domain interacts with M2i+38 globular domain

49

Inter-layer N-M1 contacts

 

IA (Å2)

Radial inter-layer contacts

  

  Interface i

Ni C-terminal lobe interacts with M1i globular domain

345

  Interface ii

Ni C-terminal lobe interacts with M1i-38 globular domain

310

  Interface iii

Ni C-terminal lobe interacts with M1i+1 globular domain

117

Inter-layer M1-M2 contacts

 

IA (Å2)

Radial inter-layer contacts

  

  Interface iv

M1i globular domain interacts with M2i globular domain

600

  Interface v

M1i globular domain interacts with M2i+1 globular domain

430

  1. aIA: interface area (buried accessible surface area upon interface formation).
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