Fig. 9: A subset of the apically located vesicles in schizonts show colocalization between AMA1 and PM X or SUB1 by immunoEM.

Synchronized, C1-treated, 48–50 h schizonts expressing either PM X-3xHA (a) or SUB1-3xHA (b) were processed as described in the methods. Thin section samples were labeled for the indicated markers and visualized by immunoelectron microscopy. Black arrows: 18 nm beads that detect the anti HA antibody, yellow arrows: 12 nm beads that detect the anti AMA1 antibody. Sections showing apical vesicles are magnified from each image. R rhoptry, N nucleus. Shown are representative images from two independent experiments.