Fig. 1: Overview of the study. | Nature Communications

Fig. 1: Overview of the study.

From: The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

Fig. 1

Japan COVID-19 Task Force (JCTF) has collected DNA, RNA, and plasma from COVID-19 cases along with detailed clinical information. A subset of n = 500 (n = 465 after QC) harboring RNA-seq data was analyzed in this study. COVID-19 disease severity was used together with RNA-seq data to perform differential gene expression and intron usage analysis (red). Imputed genotyping data with RNA-seq data was used to perform cis-e/sQTL and trans-eQTL analysis, followed by fine-mapping (for cis-QTLs), colocalization and validation with external dataset (dotted line).

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