Fig. 5: Model for regulation of LpxC degradation.
From: Regulatory mechanisms of lipopolysaccharide synthesis in Escherichia coli
a In exponential growth phase, YejM and LapB form a stable complex, and FtsH degrades LpxC slowly. b In stationary phase, LPS accumulates in the IM, displacing the LapB dimer from YejM. The liberated LapB dimer binds to FtsH, acts as an adaptor protein, and stimulates LpxC degradation.
