Fig. 5: Lysozyme structural maps showing the active site pocket.

The electron density map with the omit map displayed for the active site region of lysozyme in a the first hit structure (7TUM) and b the second hit structure (6WEC). c Shows the first (red) and second (green) hit structures superimposed and overlaid with the difference electron density (DED) map for the active site and d shows the DED maps for a representative di-sulphide bond Cys115-Cys30. No differences density is detected between the first and second hit structures. The 2Fo-Fc map at 1σ is shown in blue and difference maps at 3σ are shown in green (positive) and red (negative) density.