Table 2 Top 20 significantly upregulated genes in the human and murine SASP clusters. Multiple t-test with Benjamini–Hochberg adjustment
From: A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues
Gene | avg_log2FC | Adj. p value |
|---|---|---|
Human | ||
S100A9 | 1.974317678 | 0 |
CXCL8 | 1.817775253 | 0 |
CST3 | 1.813835295 | 0 |
TYROBP | 1.742773952 | 0 |
LST1 | 1.704456515 | 0 |
FCN1 | 1.704148119 | 0 |
FCER1G | 1.698071186 | 0 |
LYZ | 1.695879021 | 0 |
CCL3 | 1.68109761 | 0 |
S100A8 | 1.639167524 | 0 |
CTSS | 1.605107533 | 0 |
AIF1 | 1.537560282 | 0 |
S100A12 | 1.501013381 | 0 |
SAT1 | 1.475740324 | 0 |
G0S2 | 1.471768259 | 0 |
S100A11 | 1.426583167 | 0 |
PSAP | 1.412156019 | 0 |
NEAT1 | 1.402008889 | 0 |
CSTA | 1.346171061 | 0 |
SERPINA1 | 1.343012763 | 0 |
Murine | ||
Ccl2 | 1.385385456 | 4.4042E-274 |
Cxcl14 | 1.348765531 | 0 |
Cxcl12 | 1.348099221 | 0 |
Hp | 1.32967138 | 2.6772E-298 |
Trf | 1.32483506 | 6.8972E-280 |
Serping1 | 1.304871038 | 0 |
Mt1 | 1.294617837 | 0 |
Tmem176b | 1.238330075 | 0 |
Mt2 | 1.224158694 | 0 |
Igfbp4 | 1.210905773 | 0 |
Grem1 | 1.207056724 | 0 |
Cd302 | 1.195220747 | 0 |
Apoe | 1.163062993 | 0 |
Msmp | 1.16240244 | 3.2104E-194 |
Adipoq | 1.140888365 | 7.4114E-283 |
Cyr61 | 1.136426625 | 0 |
Gas6 | 1.110474329 | 0 |
Mmp13 | 1.095488296 | 0 |
Tmem176a | 1.087765581 | 0 |
sCol3a1 | 1.082720154 | 1.1707E-254 |
