Table 1 Genotypes of the selected Mtb clinical isolates strains used in this study

From: Inhibition of the Niemann-Pick C1 protein is a conserved feature of multiple strains of pathogenic mycobacteria

Strain

SpoligotypeI

ST numberII

Lineage categoryIII

Lineage numberIV

Lineage geographical locationV

232

EA14_VNM

ST139

Ancient

1

IO

346

EA14_VNM

ST140

Ancient

1

IO

372

EA14_VNM

ST141

Ancient

1

IO

281

ZERO

ST405

Ancient

1

IO

374

BEIJING

ST1

Modern

2

BJ

212

BEIJING

ST2

Modern

2

BJ

333

BEIJING

ST3

Modern

2

BJ

119

BEIJING

ST4

Modern

2

BJ

345

BEIJING LIKE

Unclassified

Modern

2

BJ

649

BEIJING LIKE

ST269

Modern

2

BJ

318

T1

ST53

Modern

4

EA

173

H1

ST62

Modern

4

EA

367

ZERO

ST405

Ancient

1

IO

440

H3

ST946

Modern

4

EA

639

H3

ST50

Modern

4

EA

293

T1

ST53

Modern

4

EA

  1. I and II Classified in accordance with the international Spoligotyping database78. III Classified based on evolutionary phylogenetic tree79. IV Classified in accordance with sequence alignment36. V. BJ. East Asian/Beijing; IO. Indo-Oceanic; EA. Euro-American.