Table 2 List of grade ≥ 3 adverse events on treatment
Grade ≥ 3 AE (>5% frequency) | Gem+Nab-P+Durva+Treme (n = 119) | Gem+Nab-P (n = 58) |
|---|---|---|
Any grade ≥3 AE | 100 (84) | 44 (76) |
Fatigue | 24 (20) | 12 (21) |
Thromboembolic event | 16 (15) | 7 (12) |
Sepsis | 13 (11) | 7 (12) |
Peripheral sensory neuropathy | 13 (11) | 7 (12) |
Diarrhea | 6 (5) | 6 (10) |
Abdominal pain | 6 (5) | 6 (10) |
Febrile neutropenia | 7 (6) | 4 (7) |
Vomiting | 7 (6) | 2 (3) |
Edema limbs | 5 (4) | 3 (5) |
Bile duct stenosis | 7 (6) | 0 (0) |
Biliary tract infections | 11 (9) | 3 (5) |
Lung infection | 6 (5) | 4 (7) |
Generalized muscle weakness | 1 (1) | 5 (9) |
Renal calculi | 2 (2) | 3 (5) |
Dyspnea | 8 (7) | 4 (7) |
Rash maculo-papular | 7 (6) | 2 (3) |
Hypertension | 3 (3) | 4 (7) |
