Fig. 3: Effects of methylphenidate and sulpiride (relative to placebo) on stimulus specificity of BOLD signal in the fusiform face area (FFA) and parahippocampal place area (PPA) during unexpected outcomes. | Nature Communications

Fig. 3: Effects of methylphenidate and sulpiride (relative to placebo) on stimulus specificity of BOLD signal in the fusiform face area (FFA) and parahippocampal place area (PPA) during unexpected outcomes.

From: Striatal dopamine dissociates methylphenidate effects on value-based versus surprise-based reversal learning

Fig. 3

Effect of methylphenidate (a; N = 85 participants) and sulpiride (b; N = 82) on stimulus-specific reversal-related signal in FFA/PPA as a function of low and high caudate nucleus kicer (median split for visualization; methylphenidate versus placebo × expectancy × caudate nucleus kicer in repeated-measures ANOVA: F(1,83) = 7.09, P = 0.009; sulpiride versus placebo × expectancy × caudate nucleus kicer: F(1,80) = 5.10, P = 0.027). Boxplots and round dots next to distribution kernels are defined as in Fig. 1c. Source data are provided with this paper. c Individually defined ROIs for the FFA (red) and PPA (blue).

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