Fig. 7: Proposed model for the role of G5C in RNA translation.
From: Structural basis for Gemin5 decamer-mediated mRNA binding
a The G5C decamer is a dimer of pentamers, with five TPR dimers bridging two pentamers. Full-length Gemin5 forms a homodecamer via G5C. b Multivalent interactions between G5C and stem-loop regions of mRNA enable high-order assembly of RNA‒protein complexes. These complexes might upregulate mRNA translation by enabling mRNA storage and preventing mRNA decay.
