Fig. 5: Putative PVC degradation pathway of strain EMBL-1.
From: Polyvinyl chloride degradation by a bacterium isolated from the gut of insect larvae
The pathway was proposed based on multiomic analyses that integrated the genomic, proteomic, transcriptomic, and metabolomic results for strain EMBL-1 during growth on PVC film. Solid arrows in the figure represented one-step reactions, and dashed arrows represented multi-step reactions. The range of ‘n’ in the formula of right upper panel was 4~24. The proteins in the green text box and oval were proteins encoded in the genome of EMBL-1. The proteins in the orange text box and oval were the proteins detected in the proteome. The blue oval proteins are the products of genes that were upregulated in the transcriptome. The above proteins are a class of proteins predicted to be involved in the degradation of PVC, and catalase-peroxidase is a functionally verified PVC-degrading enzyme (PVCase) by this study.
