Fig. 7: Blood-oxygenation level-dependent (BOLD) fMRI activation maps during contralateral forepaw stimulation. | Nature Communications

Fig. 7: Blood-oxygenation level-dependent (BOLD) fMRI activation maps during contralateral forepaw stimulation.

From: Wireless charging-mediated angiogenesis and nerve repair by adaptable microporous hydrogels from conductive building blocks

Fig. 7

a Illustration of the experimental design. Activation was triggered by electrical stimulation of the right forepaw 30 days after TBI. b Comparison of activation Z-maps obtained by group-level BOLD contrasts in the treated groups of PBS (n = 6), MBs (n = 6), CMH (n = 6) and CMH + HFMF (n = 6), respectively, superimposed on corresponding high-resolution RARE T2 images. Visualization of activation Z-maps displayed at z- threshold free and their activity in voxels within the red boundary reached the significant level threshold at Z > 2.3 (p < 0.05). Mean time courses of relative BOLD responses in contralateral (c) M1 and (d) S1FL in response to forepaw stimulation each group. The intervals of electrical stimuli are represented by yellow boxes with five repetitions. Data are represented as mean ± SEM. The average number of activated pixels across all slices representing ipsilateral (e) M1 and (f) S1FL, respectively. (n = 6, mean ± s.d., one-way ANOVA with a Tukey’s multiple-comparison test).

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