Fig. 2: Identification of BNC2 as a MF identity TF. | Nature Communications

Fig. 2: Identification of BNC2 as a MF identity TF.

From: Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis

Fig. 2

A Network-based presentation of the 25 TFs identified by our approach. The connection between TFs was provided by String108. TFs are colored according to the number of PubMed citations linking a given TF to MFs or fibrosis as detailed in the Methods section. TFs of the HOXB family were grouped together. TFs in the green background have no reported link to MFs or fibrosis. B Analysis performed as in (C) except cells were ranked according to increasing BNC2 expression levels. COL1A1 and ACTA2 expression levels are displayed using the same color scale. Ranking of 64 MF cell types is indicated at the bottom using purple horizontal bars. C Prediction of BNC2-associated functions by the Gene-module association Determination (G-MAD) tool. The top five terms (highest G-MAD scores) are shown.

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