Table 1 Demographics and Clinical Characteristics of Lean and Obese Patients
From: Interferon gamma mediates the reduction of adipose tissue regulatory T cells in human obesity
|  | Lean subjects (n = 15) | Obese subjects (n = 83) |
|---|---|---|
#Female/#Male (% Female) | 7/8 (47) | 58/25 (70) |
Age (years) | 42.9 ± 12.3 | 45.0 ± 11.3 |
BMI (kg/m2) | 23.6 ± 1.8 | 48.8 ± 8.5*** |
Fasting glucose (mg/dL) | 82.8 ± 14.5 | 90.3 ± 21.7* |
Fasting Insulin (µIU/mL) | 5.0 (1.6–6.9) | 14.5 (8.1–26.3)** |
HOMA-IR | 1.0 (0.3–1.7) | 3.1 (1.5–6.3)* |
Plasma adiponectin (ng/mL) | 9772 (5540–20851) | 5451 (3347–8752)*** |
Plasma Leptin | 27.8 ± 10.3 | 51.8 ± 43.5*** |
Systolic Blood Pressure (mmHg) | 124.4 ± 22.4 | 133.0 ± 17.1 |
Diastolic Blood Pressure (mmHg) | 70.4 ± 10.3 | 75.8 ± 8.2 |
Total Cholesterol (mg/dL) | 185.0 ± 25.3 | 176.6 ± 34.2 |
LDL Cholesterol (mg/dL) | 101.6 ± 35.7 | 93.4 ± 27.7 |
HDL Cholesterol (mg/dL) | 57.5 (45.3–76.8) | 45.5 (38.0–53.5) |
Triglycerides (mg/dL) | 117.3 ± 105.9 | 167.3 ± 76.1 |
AST | 64.7 ± 155.6 | 27.2 ± 21.3 |
ALT | 31.5 ± 9.3 | 27.9 ± 19.0 |
# Subjects on ACE inhibitor or ARB (%) | 0/15 (0) | 39/83 (47.0) |
# Subjects on Statins (%) | 0/15 (0) | 33/83 (39.8) |
# Subjects with Type 2 Diabetes Mellitus (%) | 0/15 (0) | 20/83 (24.1) |
# Subjects with Hypertension (%) | 4/15 (26.7) | 51/83 (61.4) |
# Subjects with Hyperlipidemia (%) | 0/15 (0) | 37/83 (44.6) |
