Fig. 1: Construction of bioelectronic bandage and validation of its correlation with respiratory tract vagus nerve impulses.
From: Biofeedback electrostimulation for bionic and long-lasting neural modulation
a Schematic diagram of working principle converting respiratory movement into real-time Bio-iES signals synchronized with vagus nerve impulses peak envelope, and the Bio-iES is transmitted to the defected nerve through MF-NGC. b Optical image of bioelectronic bandage showed miniaturization and flexibility. SEM image displayed a cross-section of bioelectronic bandages. c FEA analysis of potential generated in TP-hNG. d Synchronism measurement between Bio-iES signals (red line) and vagus (blue line) and phrenicus nerve impulses (orange line) peak envelope. Statistics of inspiratory duration e and exhalation duration f recorded from breathing curve (black line), vagus nerve peak envelope and phrenic nerve peak envelope and Bio-iES signals, respectively; g linear fit between Bio-iES voltage peak-to-peak and vagus nerve peak envelope potential amplitude; h linear fit between Vpp of Bio-iES and phrenic nerve peak envelope potential amplitude, black line indicated the linear fitting curves.
