Fig. 3: Spatiotemporal diffusion of Lassa virus lineages in the western Africa region and Nigeria. Maximum clade credibility (MCC) tree obtained by continuous phylogeographic inference based on 1000 posterior trees.

A separate phylogeographic analysis was performed for segments L and S as well as, in the case of the Nigerian data set, on clades II, III, and VI. These MCC trees are superimposed on 80% highest posterior density (HPD) intervals reflecting phylogeographic uncertainty. Nodes of the trees, as well as HPD regions, are coloured according to their time of occurrence, and oldest nodes (and corresponding HPD regions) are here plotted on top of youngest nodes. The trees are superimposed on maps displaying the main rivers present in the study area and classified according to their Strahler number S, which measures the importance of a river by looking at the number of upstream rivers connected to it. International borders are represented by grey dashed lines. See also Figs. S9 and S10 for visualisations clade by clade. The “MRU clade” groups the subclades circulating in the Mano River Union (MRU) and Mali (also called lineages IV and V); “NGA clade II”, “III” and “VI” correspond to the main clades circulating in Nigeria (also called lineages II, III and VI, respectively).