Fig. 5: Exocyclic olefin 1′ transfer-dehydroaromatization.
a Aliphatic exocyclic olefins. b Fused aromatic rings. c Exo-conjugated systems. d Unsymmetric cycloisomerization products. Standard conditions: The olefin (0.25 mmol), L1/Pd(TFA)2 catalyst (0.025 mmol), HBpin (0.0375 mmol), and R8 (0.5 mmol) were stirred in 2 mL of THF for 24 h at 50 °C, unless otherwise indicated. The yields of 2 and 2:3 (shown in parentheses) were determined by 1H NMR (as the average of two runs). a48 h; bas determined by GCMS (see the Supplementary Information for details); c60 °C; d2.5 equiv. of R1; eOther products are from olefin isomerization; f3 equiv. of R8; g70 °C; hwith a 9% aromatic product without OH.
