Fig. 7: Alternative classification of TETs using representative gene markers of tumor cells.
From: The immune landscape of human thymic epithelial tumors
(a-b) Dot plots depicting the relative levels of the GNB3 (a) and CHI3L1 (b) genes in total cells from each group. (c) Representative IF staining images showing GNB3 (green), CHI3L1 (red), and DAPI (nuclei, blue) in TET samples. Scale bar: 50 ÎĽm. Experiment was performed in three independent samples for each group with similar results. (d) Overall survival (OS) examined in each of the three types of TETs in the TCGA cohort. The P value was calculated using the log-rank test. (e) Schematic model summarizing the developmental patterns of three types of TETs, including interactions between different types of cells. The ligand is secreted by the cell at the beginning of an arrow, and the receptor is expressed by the cell at the end of that arrow. Source data are provided as a Source Data file.
