Table 3 Quantitative comparisons of the internal testing of 326 patients

From: Comprehensive and clinically accurate head and neck cancer organs-at-risk delineation on a multi-institutional study

Anchor OARs

UaNet

SOARS

DSC

HD (mm)

ASD (mm)

DSC

HD (mm)

ASD (mm)

BrainStem

81.6% ± 5.3%

8.8 ± 3.3

1.7 ± 0.7

83.2% ± 5.8%

9.0 ± 4.3

1.6 ± 0.8

Cerebellum

90.1% ± 9.4%

9.5 ± 6.6

1.2 ± 0.5

92.9% ± 2.2%

7.9 ± 4.8

0.9 ± 0.3

Eye_Lt

85.1% ± 13.2%

3.7 ± 1.4

0.8 ± 0.5

88.5% ± 4.9%

2.9 ± 1.0

0.3 ± 0.4

Eye_Rt

86.2% ± 9.8%

3.6 ± 1.2

0.8 ± 0.4

88.7% ± 4.8%

2.8 ± 1.1

0.3 ± 0.4

Mandible_Lt

85.0% ± 14.6%

14.7 ± 13.3

1.7 ± 4.4

89.1% ± 2.9%

5.4 ± 4.4

0.5 ± 0.4

Mandible_Rt

86.0% ± 12.3%

13.5 ± 11.6

1.5 ± 3.9

89.0% ± 3.4%

5.5 ± 4.6

0.5 ± 0.4

SpinalCord

81.5% ± 9.8%

17.1 ± 37.5

4.2 ± 14.5

86.3% ± 4.0%

4.7 ± 1.4

0.7 ± 0.2

TMJ_Lt

73.0% ± 7.0%

4.8 ± 1.6

1.2 ± 0.4

81.0% ± 9.1%

3.5 ± 1.4

0.7 ± 0.5

TMJ_Rt

75.5% ± 7.1%

4.4 ± 1.6

1.1 ± 0.4

83.6% ± 6.6%

3.4 ± 1.1

0.6 ± 0.3

Mid-level OARs

BasalGanglia_Lt

76.0% ± 7.7%

9.5 ± 3.0

1.8 ± 0.7

70.9% ± 9.5%

11.4 ± 3.6

2.3 ± 1.0

BasalGanglia_Rt

73.8% ± 9.1%

10.2 ± 2.8

2.0 ± 0.8

71.4% ± 10.1%

10.7 ± 3.3

2.2 ± 0.9

Brachial_Lt

57.5% ± 8.1%

19.8 ± 11.1

1.9 ± 1.4

60.8% ± 7.6%

21.8 ± 13.2

1.9 ± 1.7

Brachial_Rt

54.6% ± 10.1%

19.9 ± 9.7

2.0 ± 1.6

59.6% ± 7.8%

24.8 ± 11.7

2.0 ± 1.8

Const_Inf

68.2% ± 11.9%

7.2 ± 2.9

1.3 ± 0.5

70.2% ± 10.9%

5.9 ± 2.6

1.1 ± 0.5

Const_Mid

61.3% ± 10.8%

11.5 ± 5.9

1.9 ± 0.8

63.5% ± 8.7%

10.2 ± 5.5

1.7 ± 0.6

Const_Sup

58.6 ± 10.3%

11.1 ± 4.3

2.0 ± 0.9

61.2% ± 8.8%

10.6 ± 3.9

1.9 ± 0.7

Esophagus

74.2 ± 10.5%

16.3 ± 11.4

2.0 ± 2.4

72.7% ± 11.2%

28.9 ± 30.6

4.2 ± 7.2

Glottic area

58.6 ± 15.3%

9.5 ± 6.3

2.7 ± 2.1

67.8% ± 10.8%

6.1 ± 1.9

1.7 ± 0.6

GSL

68.1 ± 10.2%

8.9 ± 3.6

1.3 ± 0.7

71.3% ± 9.2%

6.7 ± 3.0

1.1 ± 0.6

OralCavity

73.4 ± 6.0%

21.2 ± 5.1

5.1 ± 1.3

75.5% ± 7.4%

19.2 ± 5.2

4.0 ± 1.6

Parotid_Lt

83.2 ± 5.8%

9.6 ± 3.3

1.4 ± 0.6

88.4% ± 4.3%

7.8 ± 4.0

0.9 ± 0.4

Parotid_Rt

82.7 ± 6.2%

10.6 ± 4.6

1.5 ± 0.7

87.7% ± 3.9%

8.4 ± 4.5

1.0 ± 0.5

SMG_Lt

79.2 ± 8.9%

7.7 ± 4.4

1.3 ± 0.6

82.0% ± 7.8%

6.5 ± 4.1

1.0 ± 0.5

SMG_Rt

77.7 ± 9.2%

7.9 ± 4.0

1.4 ± 0.8

82.2% ± 6.6%

6.4 ± 2.8

1.0 ± 0.4

TempLobe_Lt

80.9 ± 6.2%

13.9 ± 5.9

2.4 ± 0.9

82.9% ± 5.2%

13.0 ± 5.0

2.2 ± 0.7

TempLobe_Rt

81.4 ± 5.6%

13.9 ± 5.1

2.3 ± 0.8

83.4 ± 5.2%

12.1 ± 4.6

2.1 ± 0.7

Thyroid_Lt

80.0 ± 9.8%

7.5 ± 4.7

1.0 ± 0.7

82.8 ± 8.7%

7.7 ± 15.0

1.1 ± 3.5

Thyroid_Rt

80.6 ± 8.9%

7.4 ± 4.9

1.0 ± 0.9

84.1 ± 5.8%

6.3 ± 4.0

0.8 ± 0.4

S&H OARs

Cochlea_Lt

62.8 ± 15.9%

2.8 ± 1.5

0.8 ± 0.7

66.0 ± 11.4%

2.3 ± 0.7

0.6 ± 0.3

Cochlea_Rt

61.7 ± 16.1%

2.9 ± 1.6

0.8 ± 0.7

66.5 ± 10.7%

2.3 ± 0.7

0.6 ± 0.3

Hypothalamus

37.5 ± 23.1%

9.2 ± 4.2

3.0 ± 1.9

59.1 ± 11.5%

5.7 ± 2.2

1.4 ± 0.7

InnerEar_Lt

65.6 ± 11.3%

4.2 ± 1.6

1.1 ± 0.6

75.3 ± 7.9%

3.0 ± 0.7

0.6 ± 0.3

InnerEar_Rt

66.0 ± 10.4%

4.2 ± 1.4

1.1 ± 0.5

75.0 ± 7.8%

3.0 ± 0.7

0.7 ± 0.6

LacrimalGland_Lt

45.9 ± 13.7%

5.7 ± 1.4

1.6 ± 0.5

57.8 ± 9.5%

4.0 ± 0.9

0.9 ± 0.3

LacrimalGland_Rt

43.6 ± 13.9%

5.6 ± 1.3

1.6 ± 0.5

56.3 ± 10.2%

4.3 ± 1.2

1.0 ± 0.3

Lens_Lt

70.9 ± 8.9%

2.8 ± 0.7

0.6 ± 0.3

74.8 ± 9.7%

2.7 ± 0.8

0.4 ± 0.3

Lens_Rt

72.4 ± 9.7%

2.8 ± 0.7

0.5 ± 0.3

79.5 ± 8.3%

2.2 ± 0.8

0.3 ± 0.2

OpticChiasm

59.8 ± 15.8%

6.5 ± 2.4

1.4 ± 0.7

67.1 ± 11.4%

6.4 ± 2.1

0.8 ± 0.5

OpticNerve_Lt

67.6 ± 8.6%

5.2 ± 2.6

0.8 ± 0.3

69.8 ± 7.3%

4.8 ± 3.1

0.7 ± 0.3

OpticNerve_Rt

67.0 ± 9.7%

5.4 ± 4.6

0.8 ± 0.5

68.2 ± 7.1%

4.5 ± 3.0

0.7 ± 0.3

PinealGland

50.6 ± 14.0%

4.0 ± 1.4

1.1 ± 0.5

55.6 ± 10.1%

3.6 ± 1.3

0.9 ± 0.4

Pituitary

60.2 ± 16.0%

4.1 ± 1.3

1.0 ± 0.4

69.6 ± 12.1%

3.4 ± 1.2

0.6 ± 0.4

Average Anchor

82.7%

8.9

1.6

86.9%

5.0

0.7

Average Mid-level

72.1%

11.8

1.9

74.6%

12.4

1.8

Average S&H

59.4%

4.7

1.2

67.2%

3.7

0.7

Average all

69.8%

8.8

1.6

74.8%

7.9

1.2

  1. Note: Bold values represent the statistically significant improvements (calculated using Wilcoxon matched-pairs signed rank test) as compared between UaNet and SOARS. When the mandible is considered as a single OAR instead of left and right mandible, SOARS achieves the mean DSC, HD and ASD of 89.1%, 5.4 mm, and 0.5 mm, respectively. Similarly, when the thyroid is considered as a single OAR instead of left and right thyroid, SOARS achieves the mean DSC, HD, and ASD of 83.5%, 7.0 mm, and 1.0 mm, respectively.
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