Fig. 4: Characterization of 3D morphology of different sucrose fractions using high-resolution AFM imaging.
From: Small soluble α-synuclein aggregates are the toxic species in Parkinson’s disease
A–E Representative AFM images of the sucrose fractions including zoom-in snapshots of individual aggregates. F, G Boxplot of the height (N = 527 for 10%, N = 2785 for 20%, N = 6884 for 30%, N = 2473 for 40% and N = 7333 for 50%) and convoluted diameter (N = 533 for 10%, N = 2786 for 20%, N = 6885 for 30%, N = 2445 for 40% and N = 6585 for 50%) (G) of each fraction. The limits of the box representing the 25th–75th quartile range and the horizontal line matching the median and the whiskers are mean + 1 STD. Each individual colour is representing a distinct sucrose fraction (orange = 20%, green = 30%, blue = 40%, violet = 50%). The datasets represents one technical repeat. Source data are provided as a Source Data file.
