Fig. 5: Experimental validation of the guidance model.
From: Predictive model for cytoneme guidance in Hedgehog signaling based on Ihog- Glypicans interaction
a P compartment cells overexpressing Ihog confronted to clones also overexpressing Ihog. White arrows indicate those cytonemes to be simulated. b Guidance field estimation (green small arrows) of the experimental conditions eliminating selected cytonemes. c In silico predicted trajectories for the simulated cytonemes. a’ P compartment cells overexpressing Ihog confronted with clones overexpressing Dally. White arrows show the cytonemes to be simulated. b’ Guidance field estimation (green small arrows) of the experimental conditions eliminating selected cytonemes. c’ In silico predicted trajectories for the simulated cytonemes. Scale bars: 15μm.
