Fig. 6: Wild type Ihog, Dally and Dlp spatial distributions at the basal plane of wing imaginal discs.
From: Predictive model for cytoneme guidance in Hedgehog signaling based on Ihog- Glypicans interaction
a Wild type Ihog basal distribution in a Bac.IhogGFP wing disc. b Wild type Dlp basal distribution obtained by immunohistochemistry. c Wild type Dally basal distribution in a Dally.trap.YFP wing disc. d Characterization of Ihog (green), Dlp (blue) and Dally (red) profiles at the basal plane of imaginal wing discs. Dotted lines represent the average profile and shaded area and their experimental variability, quantified by the standard deviation over different samples (nIhog = 17, nDlp = 17, nDally = 19). e Surface representation of wild-type Ihog, Dlp and Dally basal patterns in the marked elliptical area of the wing pouch. These quantified 2D patterns (matrices) are the numerical inputs for the computational wild-type simulations. Scale bars: 30 μm.
