Fig. 4: Phage-antibiotic synergy assay results. | Nature Communications

Fig. 4: Phage-antibiotic synergy assay results.

From: Bacteriophage-antibiotic combination therapy against extensively drug-resistant Pseudomonas aeruginosa infection to allow liver transplantation in a toddler

Fig. 4

Activities of phage PNM (at multiplicity of infection [MOI] 1.0) and a/d colistin (0.5 mg/L), b/e aztreonam (8 mg/L), and c/f gentamycin (2 mg/L), as well as combinations of phage PNM and these antibiotics against Pseudomonas aeruginosa isolate Pa1BS (ac) and Pa7BS (d–f) were determined using an OmniLog® system. Bacterial proliferation is presented through relative units of cellular respiration. Efficacious phages, antibiotics, and combinations thereof, suppress bacterial proliferation. Results are presented as mean values of three experiments (biological replicates) with error bars representing the standard deviations of the means. Source data are provided as a Source Data file.

Back to article page