Fig. 2: EphA2 deficiency reduces renal neutrophil and monocyte recruitment, but increases DC accumulation during candidiasis.

a, b Level of indicated cytokines in kidneys after 3 days of infection. N = 8; combined data of two independent experiments. Two-tailed Mann–Whitney Test. c Accumulation of neutrophils, monocytes, and macrophages (total numbers) in the kidney of wild type and Epha2^–/– mice after 3 days of infection. N = 5, combined data of two independent experiments. ns; No Significance. Two-tailed Mann–Whitney Test. d Percent of macrophages, neutrophils, and monocytes of CD11b⁺ cells. N = 5, combined data of two independent experiments. ns, no significance. Two-tailed Mann–Whitney Test. e, f Representative flow cytometry plots of MHCII expression and frequencies of MHCII-expressing cells in infected kidneys after 3 days of infection. N = 5; combined data of two independent experiments. Two-tailed Mann–Whitney Test g Accumulation of CD11b⁺ and CD11b^– dendritic cells in kidneys of wild type and Epha2^–/– mice after 3 days of infection (N = 5). Two-tailed Mann–Whitney Test. Results are median ± SEM.