Fig. 4: Acyclic stereocontrolled synthesis of eight possible isomers with three adjacent stereogenic centers.
From: Stereodivergent dehydrative allylation of β-keto esters using a Ru/Pd synergistic catalyst
Condition A: [3aa] = 0.1 M, K-selectride 0.35 M, THF, −78 °C, 12 h; Condition B: [3aa] = 0.1 M, Zn(BH4)2 0.1 M, CH2Cl2-Et2O, 0 °C, 6 h. THF: tetrahydrofuran.
