Fig. 3: Electrochemical asymmetric allylic 4-pyridinylation of 4.
From: Palladium-catalyzed asymmetric allylic 4-pyridinylation via electroreductive substitution reaction
aConditions: 4 (0.2 mmol), 2a (0.6 mmol), PdCl2 (10 mol%), L2 (12 mol%), MeCN/MeOH 5:1 (v/v), Et4NCl (0.1 M), Zn(+)|GF(-), 5 mA/cm3, 5 h, 35 °C; isolated yields of branched products are reported; B/L were determined by with 1H NMR analyses of crude reaction mixture; Ee values were determined by HPLC on a chiral stationary phase. bCurrent density, 8 mA/cm3.
