Table 2 Effect of Vaccination

From: Household transmission of SARS-CoV-2 Omicron variant of concern subvariants BA.1 and BA.2 in Denmark

 

Susceptibility

Infectiousness

 

(Household contacts)

(Primary case)

 

Omicron BA.2 households

Omicron BA.1 households

Omicron BA.2 households

Omicron BA.1 households

Unvaccinated

1.12

1.27

1.19

0.98

 

(1.03–1.22)

(1.17–1.39)

(1.08–1.31)

(0.89–1.08)

Fully vaccinated

ref

ref

ref

ref

 

(.)

(.)

(.)

(.)

Booster vaccinated

0.81

0.69

0.86

0.82

 

(0.75–0.87)

(0.64–0.75)

(0.78–0.94)

(0.75–0.91)

  1. Notes: This table shows odds ratio (OR) estimates of susceptibility and infectiousness by vaccination status. Number of observations=50,588; Number of households=22,678. Column 1 shows the susceptibility to infection based on the vaccination status of the household contacts, conditional on living in a household infected with BA.2. Column 2 shows the susceptibility to infection based on the vaccination status of the household contacts, conditional on living in a household infected with BA.1. Column 3 shows the infectiousness based on the vaccination status of the primary case, conditional on living in a household infected with BA.2. Column 4 shows the infectiousness based on the vaccination status of the primary case, conditional on living in a household infected with BA.1. Note that all estimates are from the same model, but with a different reference category across column 1-4. The estimates are adjusted for age and sex of the primary case, age and sex of the household contact, size of the household, and primary case sample date. The estimates are furthermore adjusted for vaccination status of the household contact and primary case interacted with the household subvariant. 95%-confidence intervals are shown in parentheses with cluster-robust standard errors at the household level. The odds ratio estimates for the full model are presented in the appendix Table S12, column I. Figure S5 presents the estimates with different contrasts and reference categories.
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