Fig. 6: Polypeptide exit tunnel and membrane contacts. | Nature Communications

Fig. 6: Polypeptide exit tunnel and membrane contacts.

From: Structure of a mitochondrial ribosome with fragmented rRNA in complex with membrane-targeting elements

Fig. 6

a Comparison of the density maps between P. magna and H. Sapiens mitoribosomes. The maps were filtered to 10 Å and aligned on the LSU. mL105 (P. magna) shown in red. Zoomed panels illustrate the position of mL105 at the tunnel exit. mL128 anchored constricts the path. b Comparison of the tunnel exit between P. magna, H. Sapiens, T. thermophila, and E.coli shows that mL105 (P. magna, T. thermophila), mL45 (H. Sapiens), and Ffh M-domain (E. coli) occupy similar positions in different ribosomes. In addition, relative positions of mL128 (P. magna) and mL45-α0 (H. sapiens) are similar. The exit regions are indicated with a yellow background.

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