Fig. 4: Association of AP sites with sequence variants. | Nature Communications

Fig. 4: Association of AP sites with sequence variants.

From: Complex genomic patterns of abasic sites in mammalian DNA revealed by a high-resolution SSiNGLe-AP method

Fig. 4

a Overlap of AP sites and sequence variants across the 71 mouse samples. b Odds ratios of overlap of AP sites with sequence variants in HeLa (6 biological replicates) and K562 (3 biological replicates) cell lines. Data are presented as mean values +/− SD. c Overlap between AP sites and the C alleles for the 3 indicated variant types found across 6 biological replicates of HeLa cell line. The numbers above connecting lines are p-values calculated by one-sided paired t test. Box plots indicate median (middle line), 25th, 75th percentile (box) and 1.5× interquartile range (whiskers) as well as outliers (single points, a) or each individual data (single points, c). Source data are provided as a Source data file.

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